Assignment Help - homework help

  Pathogenesis of vibrio

Pathogenesis of vibrio:

The Cholera vibrios are ingested in drink or food and the dosage is little. After passing the acidity of the stomach, the organisms start to multiply in the alkaline atmosphere in small intestine. With the aid of enzymes generated by the organisms, they penetrate the mucous layer and adhere to the enterocyte surface.

Vibrio Cholerae Enterotoxin:

The main virulence factor in vibrio cholerae is cholera toxin. This is a heat labile enterotoxin with a molecular weight of around 84,000, having sub units A (M.W. 28,000) and B. The sub-unit-B joins on Ganglio side GH1 that serves as the mucosal receptor, and it promotes entry of sub-unit A into the cell. The A sub-unit gives the toxigenic activity intracellularly after proteolytic cleavage into 2 peptides A1 and A2. A1 is the active part of the molecule.

Activation of A1 sub unit raises the levels of intracellular c AMP and outcomes in prolonged hyper secretion of water and electrolytes. There is raised sodium-dependent chloride secretion and sodium and chloride absorption is inhibited. As an outcome diarrhoea takes place, with 20-30 litres per day loss of water.

 

Latest technology based Biology Online Tutoring Assistance

Tutors, at the www.tutorsglobe.com, take pledge to provide full satisfaction and assurance in Medical Bacteriology help via online tutoring. Students are getting 100% satisfaction by online tutors across the globe. Here you can get homework help for Medical Bacteriology, project ideas and tutorials. We provide email based Medical Bacteriology help. You can join us to ask queries 24x7 with live, experienced and qualified online tutors specialized in Medical Bacteriology. Through Online Tutoring, you would be able to complete your homework or assignments at your home. Tutors at the TutorsGlobe are committed to provide the best quality online tutoring assistance for Microbiology Homework help and assignment help services. They use their experience, as they have solved thousands of the Biology assignments, which may help you to solve your complex issues of Medical Bacteriology. TutorsGlobe assure for the best quality compliance to your homework. Compromise with quality is not in our dictionary. If we feel that we are not able to provide the homework help as per the deadline or given instruction by the student, we refund the money of the student without any delay.
Home | Company Overview | Services | Discover Q&A | Sitemap | Contact Us | T & C | Refund Policy | Copyright Policy | Blog | Q&A | Directory

©TutorsGlobe All rights reserved 2022-2023.