Ig G

Ig G:

Ig G has two similar antigen binding sites and is bivalent. There are four subclasses that is Ig G1,Ig G2, IgG3 and IgG4. Ig G is the main antibody in secondary immune response. It plays a significant role in defense against bacteria, viruses. It too neutralizes toxins. It crosses placenta and is found in big amounts in newborns.

Ig G subclasses:

Structure: they vary in number and arrangement of inter-chain disulphide bonds.

 

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