Classification of Herpes Virus:
Classification of the several members of the herpes viridae is complex.
1. Alpha herpes viruses:
They are growing rapid with an associatively short replicating cycle (12 to 18 hours) and are Cytolytic with a variable host range. They tend to establish latent infection in sensory nerve ganglia. Example, HSV 1 & 2, VZV.
2. Beta herpes viruses:
They are very slow growing viruses with a long replicating cycle (i.e., more than 24 hours) and contain a narrow host range. They tend to generate enlargement of infected cells (i.e., cytomegaly) and cause latent infection of salivary glands and kidneys. Example, EBV & HHV 8.
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