Acute HIV infection

Acute HIV infection:

This is otherwise termed as seroconversion illness. The patient with HIV infection for 2 to 6 weeks experience symptoms similar to glandular fever and adenopathy. It is recognized in 5 to 10 percent of patients. Recovery takes place within weeks. Initially HIV antibodies are negative and mount throughout the course of illness.

Clinical latency:

Every HIV infected individuals pass via a stage of asymptomatic infection or else termed as clinical latency, that extends up to numerous years. Patients are infectious and tests for HIV antibodies are positive. Viral multiplication occurs all through the period of clinical latency. The CD4 T cell count reduces steadily and whenever the count falls to 200 or less full blown AIDS generates.

Persistent generalized lymphadenopathy:

The persistence of enlarged lymph nodes in two or more non contiguous more inguinal sites for more than 3 months, in the absence of any other causes of adenopathy like lymphomata is termed as persistent generalized lymphadenopathy.

Constitutional diseases:

Patients in this class suffer from a range of constitutional symptoms persistent diarrhea, fever, and marked weight loss or with minor opportunistic infections. The patients are rigorously ill and present with generalized lymphadenopathy and splenomegaly. Such symptoms are termed as AIDS associated complex (i.e., ARC) and the patients might progress to AIDS.

Neurologic disease:

Approximately 90% of HIV patients contain neurologic diseases like toxoplasmosis, cryptococcosis and lymphoma of the central nervous system. Different neurological syndromes like subacute encephalitis, vacuolar myelopathy, aseptic meningitis and dementia complex frequently takes place in patients with AIDS.

 

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