Galactosemia:
Galactosemia is an inherited disorder, where there is inability to convert galactose to glucose in a general way. The incidence of this disease is approximately 1 in 18,000 live births.
Causes:
Enzyme deficiency in galactose metabolic pathway originates the galactosemia. The pathway for translation of galactose to glucose is displayed in the below figure.
Diagram: Metabolism of Galactose
In galactosemia, there is incapability to metabolize galactose that may be caused through the enzyme deficiency of a = galactokinase, b = UDP Galactose 1 - phosphate uridyl transferase.
Symptoms:
The absence of galactose 1-phosphate uridyl transferase is clinically significant. Because of the enzyme defect galactose accumulates in blood and is decreased through aldose reductase in the eye to the corresponding galactitol that causes cataract.
The normal condition is more severe if it is because of a defect in galactose 1 - phosphate uridyl tranferase, because galactose 1-phosphate accumulates and depletes the liver of inorganic phosphate. Finally liver failure and mental deterioration results.
Infants emerge normal at birth but after that they show failure to thrive and become lethargic. They have often vomitting and hypoglycemia. Later than the 2 - 3 months of age the liver might depict fatty infiltration and go ahead to cirrhosis (non functioning of liver cells). Galactosemia at this age is related with mental retardation because of accumulation of galactose and galactose 1-phosphate in cerebral cortex. Thus, the galactosemic child fails to grow up and suffer from liver damage and mental retardation.
Latest technology based Biology Online Tutoring Assistance
Tutors, at the www.tutorsglobe.com, take pledge to provide full satisfaction and assurance in Galactosemia homework help via online tutoring. Students are getting 100% satisfaction by online tutors across the globe. Here you can get homework help for Galactosemia, project ideas and tutorials. We provide email based Galactosemia homework help. You can join us to ask queries 24x7 with live, experienced and qualified online tutors specialized in Galactosemia. Through Online Tutoring, you would be able to complete your homework or assignments at your home. Tutors at the TutorsGlobe are committed to provide the best quality online tutoring assistance for Biology homework help and assignment help services. They use their experience, as they have solved thousands of the Biology assignments, which may help you to solve your complex issues of Galactosemia. TutorsGlobe assure for the best quality compliance to your homework. Compromise with quality is not in our dictionary. If we feel that we are not able to provide the homework help as per the deadline or given instruction by the student, we refund the money of the student without any delay.
We offer First-class Graph Theory Assignment Help service at most viable prices which always make you stand out from your peers.
Reactions of Quinolines tutorial all along with the key concepts of Physical and Chemical Properties of Quinoline, Electrophilic Substitution, Nucleophilic Addition/Substitution of of Quinoline
tutorsglobe.com clinical manifestations of lyme disease assignment help-homework help by online lyme disease tutors
our top-rated biochemistry assignment help service offer ideal solutions drafted by qualified tutors at low prices and ensure a++ grades.
Lasers tutorial all along with the key concepts of Characteristics of Laser radiation, Directionality, Coherence, Emission and Absorption of Light, Stimulated Emission of Light, Absorption of Light, Elements of a Laser, Applications of Lasers
Theory and lecture notes of Determining Internal Node Values all along with the key concepts of Variational Principles, finite element solution, Application to the steady state heat equation. Tutorsglobe offers homework help, assignment help and tutor’s assistance on Determining Internal Node Values
Uniform Cost Search comprising the key concepts of Iterative Depending Search, Bidirectional Search, Informed Search, Best First Search, A star Search and Flood Fill Algorithm
Optimal Costing System is dissimilar from entity to entity. It relies on an in-depth analysis of costs and advantages related with designing of an appropriate costing system.
Potential for Continuous Charge Distribution and Energy tutorial all along with the key concepts of Potential due to an Infinite Line Charge, Equipotential surface of a Uniformly Line Charge and Electrostatic Potential Energy
tutorsglobe.com artificial pacemaker assignment help-homework help by online medical lab methods tutors
Infrared radiation is abbreviated as IR radiation is electromagnetic radiation with a wavelength among 0.7 and 300 micrometers, that equates to a frequency range among about 1 and 430 THz.
tutorsglobe.com respiration assignment help-homework help by online plant physiology tutors
gramophone is a type of record player. the sound that is stored in the place is converts in to an electrical note through a tone arm.
approximately all brands of mixie will be built-in with an overload protector. in case of overloading or harsh fluctuation, the overload protector will trip automatically not manually.
Free GCSE Study Guide, GCSE Test Papers, GCSE Practice papers, GCSE Test pattern and general information, Find GCSE exam information and resource, material free at Tutorsglobe.com
1958971
Questions Asked
3689
Tutors
1443853
Questions Answered
Start Excelling in your courses, Ask an Expert and get answers for your homework and assignments!!