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Similar species with reproduction contain similar genomes

Can two normal individuals of similar species with sexual reproduction contain similar genomes and similar karyotypes? How the human karyotype is generally symbolized?

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Apart from for clones (that is, individuals made from nucleus transplantation, similar to the Dolly sheep) and monozygotic twins, it is much improbable the genomes of two individuals of similar species and produced by sexual reproduction to be similar. Nevertheless the karyotypes of two normal individuals of similar species and of similar sex are always the same. The human normal karyotype is symbolized by the formula 44+XY for men and 44+XX for women.

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