Progressive loss of axonal myelin sheath

Question

Write down some diseases which are characterized by the progressive loss of axonal myelin sheath?

Answer 1

Multiple sclerosis is severe disease caused by the progressive destruction of myelin sheath in central nervous system. The Guillain-Barré disease is because of destruction of myelin sheath in peripheral nervous system caused by autoimmunity (attack by own immune system). The genetic deficiency in formation or preservation of myelin sheath is an X-linked inheritance which is known as adrenoleukodystrophy. The movie “Lorenzo’s Oil” featured a boy with this disease and his father's dramatic search for treatment.