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Mechanism of the inflammation work

How does the mechanism of the inflammation work?

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Whenever injury of some tissue takes place the histamine and other vasoactive substances known as the mediators of Inflammation, are released, they may cause vasodilation and blood flow to the affected site increases. Granulocyte leukocytes are present within the blood are attracted to the site of injury by substances called as chemotactic factors also liberated by the injured tissue and by active granulocytes in the area. The granulocytes exit from the capillaries through the diapedesis, that is, using pseudopods. Macrophages present within the region are also activated. These cells flood the extracellular space of the affected area trying to destroy or remove the harmful agents, in order to prevent the tissue necrosis and to isolate the damaged tissue.

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