How synaptic transmissions among neurons occur
How synaptic transmissions among neurons occur?
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The propagation of action potential all along the axon reaches the area immediately anterior to the presynaptic membrane causing its permeability to calcium ions to modify and such ions to enter the cell. In presynaptic area of the axon there are numerous neurotransmitter-repleted vesicles which by means of exocytosis activated by the calcium influx discharge the neurotransmitters into the synaptic cleft. The neurotransmitters then join to particular receptors of the postsynaptic membrane. (That is, the binding of neurotransmitters to their receptors is reversible, that is, the neurotransmitters are not consumed subsequent to the process.) With the binding of neurotransmitters to the postsynaptic receptors, the permeability of postsynaptic membrane is modified and the depolarization which will lead to the first action potential of the postsynaptic cell starts.
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