Explain nucleic acids
Explain nucleic acids? Describe the historic origin of this name?
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RNA and DNA, the nucleic acids, are the molecules accountable for the hereditary information which commands the protein synthesis in the living beings. The word “nucleic” derives from the fact that they were introduced (by the Swiss biochemist Friedrich Miescher, in the year 1869) in the cell nucleus. In that time, it was not recognized that such substances composed the hereditary information.
BLOSUM Matrices: Blosum is Blocks Substitution matrices, derived based on substitution frequencies for all pairs of amino acids within a group. This is also developed by Dayhof
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