Diabetes mellitus and insipidus
State the difference between diabetes mellitus and diabetes insipidus? Specify the attribute of diabetes insipidus?
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Diabetes mellitus refers to the disease caused due to liberation of the deficient insulin through the pancreas or by impaired capturing of this hormone by the cells. Diabetes insipidus is the disease which is caused by the deficient ADH secretion by the pituitary (hypophysis) or also by impaired sensitivity of kidneys to this hormone. In the diabetes insipidus, the blood lacks ADH and so the tubular resorption of the water in the kidneys is decreased and a large volume of urine is generated. The patient urinates a lot and many times a day, a sign which is also accompanied by the polydipsia which includes increased thirst and exaggerated ingestion of water and sometimes by the dehydration.
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In ancient Greece, father of the Medicine, Hypocrates, explained the phenomenon of diagnosing diabetes mellitus by tasting the patient's urine. Specify the physiological explanation for this archaic method?
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