Action mechanism of the antiretroviral drugs

Question

Explain the action mechanism of the antiretroviral drugs termed as protease inhibitors that are utilized against HIV infection?

Answer 1

Protease inhibitors are several of the antiretroviral drugs utilized to treat HIV infection. Protease is an enzyme essential for the assembling of HIV subsequent to the synthesis of its proteins in the host cell. The protease inhibitor joins to the activation center of the enzyme blocking the making of the enzyme-substrate complex and the enzyme activity therefore impairing the viral replication.